Let Us Give it a Trial: Methods in PE

Co-Moderator(s)

• 

  Jessica Franklin, PhD (she/her/hers)

  Principal Consultant, Real-World Evidence
  Optum Epidemiology
  Marietta, United States
• 

  Soko Setoguchi, MD, DrPH, FISPE

  Professor of Medicine and Epidemiology
  Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ
  New Brunswick, United States

Presentations:

• 8:00 AM – 8:15 AM ADT

  Conditions for Unbiased Complete Case Analysis in External Control Arms: A Simulation Study
  

  Presenting Author: Michael Andrew Webster-Clark, PharmD, PhD – McGill University, Department of Epidemiology, Biostatistics, and Occupational Health
• 8:15 AM – 8:30 AM ADT

  Large-scale empirical identification of candidate comparators for pharmacoepidemiological studies
  

  Presenting Author: Justin Bohn, ScD – Johnson & Johnson
• 8:30 AM – 8:45 AM ADT

  A Meta-analysis of bias in Non-Small Cell Lung Cancer external control validation studies using PFS and real-world PFS endpoints
  

  Presenting Author: Michael Bretscher, MSc, PhD – F. Hoffmann-LaRoche Ltd
• 8:45 AM – 9:00 AM ADT

  Evaluation of methods for building a hybrid real-world (RW) control arm for baricitinib Phase IIB randomized controlled trial (RCT) in patients with rheumatoid arthritis (RA)
  

  Presenting Author: Heather Litman, PhD – CorEvitas, LLC
• 9:00 AM – 9:15 AM ADT

  A Bayesian Framework to Summarize Negative Control Outcome Models Assessing the Comparability of Patients Initiating Migraine Preventive Medications
  

  Presenting Author: Shia T. Kent, PhD – Amgen
• 9:15 AM – 9:30 AM ADT

  Using Negative Control Outcomes to Identify Unmeasured Confounding in a Self-Controlled Risk Interval Study Evaluating the COVID-19 Vaccine Myocarditis Safety Signal
  

  Presenting Author: Sophie H. Bots, PhD (she/her/hers) – Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands